What is apparent is that ictal and interictal events of a given seizure type may have different relationships to sleep. Currently, we do not know which, if any, of the mechanisms involved in IEDs underlie sleep and/or epilepsy. This discordance between cortex and hippocampus suggests crucial differences in spike synchronization mechanisms between these two regions. ![]() In contrast, at NREMS 3 & 4, hippocampal spikes are suppressed and reach relative maximum in NREMS 2. Epilepsies with random appearance (during the wake–sleep cycle) are more likely of symptomatic etiology, variable age onset, and relatively worse prognosis.Īlthough TLE patients have mostly daytime seizures, their EEG interictal epileptiform discharges (IEDs) are more often (and from more extensive neocortical areas) seen in NREMS stages 3 & 4 than in awake or REMS. Awakening epilepsies are usually idiopathic or hereditary, with onset in childhood and usually a benign course. ![]() Typical absences appear particularly prone to present during drowsiness and transitions between sleep and arousal states. Of the epilepsies associated with awakening, most common are juvenile myoclonic epilepsy, absence seizures, and epilepsy with grand mal seizures on awakening. Seizures often present in children's sleep as continuous spike and wave discharges (SWD), or poly-SWD (as in Lennox–Gastaut syndrome), indicate predominantly nocturnal types of epilepsy. Benign but not uncommon seizures, like those of Panayiotopoulos syndrome, tend also to occur during sleep. Patients with seizures arising from occipital or parietal lobes have rare sleep-onset seizures. In contrast, temporal lobe epilepsies (TLEs) do not show clear day–night preference. This is also the case with benign Rolandic epilepsy of childhood. Among types of partial epilepsy, seizures of frontal lobe epilepsy (nocturnal FLE) typically arise during NREMS – most often in stage 2 – and never during REMS. ![]() Nocturnal epilepsies are either idiopathic or hereditary and have variable course. Kostopoulos, in Encyclopedia of Basic Epilepsy Research, 2009 The Clinical Problem and Questions from the Bedside
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |